生物医药研究院

顾强帅

生物医药研究院

研究副教授

guqs@sustech.edu.cn


教育经历

2013  香港大学,博士

2008  中国科学技术大学,学士


工作经历

2020-至今     南方科技大学前沿与交叉科学研究院,研究副教授

2017-2020     南方科技大学前沿与交叉科学研究院,研究助理教授

2017             南方科技大学化学系,研究助理

2016-2017    南方科技大学化学系,访问学者

2014-2016    香港大学化学系,博士后

2012-2014    香港大学化学系,研究助理


交叉研究领域

主要从事有机合成方法学,天然产物和活性小分子的全合成、衍生化。在此基础之上对有机小分子进行活性表征,对有生物活性的分子进行构效关系研究,并利用化学生物学的手段进行生物活性机理研究,以期发现具有药物开发前景的先导化合物。


所获荣誉:

深圳市海外高层次“B类”人才(孔雀计划B类) 


代表文章

1. Chi Zhang, Zhong-Liang Li, Qiang-Shuai Gu*, and Xin-Yuan Liu*, “Catalytic Enantioselective C(sp3)–H Functionalization Involving Radical Intermediates” Nat. Commun. 2021, 12, 475.

2. Zhang-Long Yu, Yong-Feng Cheng, Na-Chuan Jiang, Jian Wang, Li-Wen Fan, Yue Yuan, Zhong-Liang Li, Qiang-Shuai Gu*, Xin-Yuan Liu*, “Desymmetrization of Unactivated Bis-alkenes via Chiral Brønsted Acid-Catalysed Hydroamination” Chem. Sci. 2020, 11, 5987.

3. Yang Zeng, Xiao-Dong Liu, Xian-Qi Guo, Qiang-Shuai Gu*, Zhong-Liang Li*, Xiao-Yong Chang, Xin-Yuan Liu*, “Cu/Chiral Phosphoric Acid-Catalyzed Radical-Initiated Asymmetric Aminosilylation of Alkene with Hydrosilane” Sci. China Chem. 2019, 62, 1529.

4. Na Wang, Liu Ye, Zhong-Liang Li, Lei Li, Zhuang Li, Hong-Xia Zhang, Zhen Guo, Qiang-Shuai Gu*, Xin-Yuan Liu*, “Hydrofunctionalization of Alkenols Triggered by the Addition of Diverse Radicals to Unactivated Alkenes and Subsequent Remote Hydrogen Atom Translocation” Org. Chem. Front. 2018, 5, 2810.

5. Zhuang Li, Xian-Yan Cheng, Ning-Yuan Yang, Ji-Jun Chen, Wen-Yue Tang, Jun-Qian Bian, Yong-Feng Cheng, Zhong-Liang Li, Qiang-Shuai Gu*, Xin-Yuan Liu*, “A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)–C(sp2) Cross-Coupling with Chiral Multidentate N,N,P-Ligand” Organometallics 2021, 40, 2215.

1. Chi Zhang, Zhong-Liang Li, Qiang-Shuai Gu*, and Xin-Yuan Liu*, “Catalytic Enantioselective C(sp3)–H Functionalization Involving Radical Intermediates” Nat. Commun. 2021, 12, 475.

2. Zhang-Long Yu, Yong-Feng Cheng, Na-Chuan Jiang, Jian Wang, Li-Wen Fan, Yue Yuan, Zhong-Liang Li, Qiang-Shuai Gu*, Xin-Yuan Liu*, “Desymmetrization of Unactivated Bis-alkenes via Chiral Brønsted Acid-Catalysed Hydroamination” Chem. Sci. 2020, 11, 5987.

3. Yang Zeng, Xiao-Dong Liu, Xian-Qi Guo, Qiang-Shuai Gu*, Zhong-Liang Li*, Xiao-Yong Chang, Xin-Yuan Liu*, “Cu/Chiral Phosphoric Acid-Catalyzed Radical-Initiated Asymmetric Aminosilylation of Alkene with Hydrosilane” Sci. China Chem. 2019, 62, 1529.

4. Na Wang, Liu Ye, Zhong-Liang Li, Lei Li, Zhuang Li, Hong-Xia Zhang, Zhen Guo, Qiang-Shuai Gu*, Xin-Yuan Liu*, “Hydrofunctionalization of Alkenols Triggered by the Addition of Diverse Radicals to Unactivated Alkenes and Subsequent Remote Hydrogen Atom Translocation” Org. Chem. Front. 2018, 5, 2810.

5. Zhuang Li, Xian-Yan Cheng, Ning-Yuan Yang, Ji-Jun Chen, Wen-Yue Tang, Jun-Qian Bian, Yong-Feng Cheng, Zhong-Liang Li, Qiang-Shuai Gu*, Xin-Yuan Liu*, “A Cobalt-Catalyzed Enantioconvergent Radical Negishi C(sp3)–C(sp2) Cross-Coupling with Chiral Multidentate N,N,P-Ligand” Organometallics 2021, 40, 2215.


联系方式

guqs@sustech.edu.cn