生物医药研究院

向少华

生物医药研究院

研究副教授

xiangsh@sustech.edu.cn

教育经历

2015       南洋理工大学（新加坡） 博士

2009       厦门大学 硕士

2006       厦门大学 学士

工作经历

2020.11-至今 南方科技大学前沿与交叉科学研究院 研究副教授

2017.9-2020.10 南方科技大学前沿与交叉科学研究院 研究助理教授

2015.2-2017.9 深圳华大基因研究院 产品经理

交叉研究领域

不对称有机催化与轴手性化学及手性药物分子的后期不对称修饰技术开发。

所获荣誉

深圳市海外高层次“B类”人才（孔雀计划B类）

代表文章

1.Junxian Yang, Ji-Wei Zhang, Wen Bao, Sheng-Qi Qiu, Shaoyu Li, Shao-Hua Xiang*, Jun Song, Junmin Zhang*, Bin Tan*. Chiral Phosphoric Acid-Catalyzed Remote Control of Axial Chirality at Boron–Carbon Bond. J. Am. Chem. Soc. 2021, 143, DOI: 10.1021/jacs.1c05079.

2.Song Chen, Ya-Nan Li, Shao-Hua Xiang*, Shaoyu Li*, Bin Tan*. Electrochemical Phenothiazination of Naphthylamines and Its Application in Photocatalysis. Chem. Commun. 2021, 57, DOI: 10.1039/d1cc03276c.

3.Ji-Wei Zhang, Shao-Hua Xiang*, Shaoyu Li, Bin Tan*. Copper‐Catalyzed Synthesis of Axially Chiral Biaryls with Diaryliodonium Salts as Arylation Reagents. Molecules 2021, 26, 3223.

4.Jun Kee Cheng†, Shao-Hua Xiang†, Shaoyu Li†, Liu Ye†, Bin Tan*. Recent Advances in Catalytic Asymmetric Construction of Atropisomers. Chem. Rev. 2021, 121, 4805. (Equal contribution).

5.Bing-Chao Da†, Shao-Hua Xiang†, Shaoyu Li†, Bin Tan*. Chiral Phosphoric Acid Catalyzed Asymmetric Synthesis of Axially Chiral Compounds. Chin. J. Chem. 2021, 39, 1787. (Equal contribution).

6.San Wu, Shao-Hua Xiang, Shaoyu Li, Wei-Yi Ding, Lei Zhang, Peng-Ying Jiang, Zi-An Zhou, Bin Tan*. Urea Group-Directed Organocatalytic Asymmetric Versatile Dihalogenation of Alkenes and Alkynes. Nat. Catal. 2021, 4, 692.

7.Jian-Hui Mao, Yong-Bin Wang, Limin Yang, Shao-Hua Xiang, Quan-Hao Wu, Yuan Cui, Qian Lu, Jie Lv, Shaoyu Li, Bin Tan*. Organocatalyst-Controlled Site-Selective Arene C-H Functionalization. Nat. Chem. 2021, 13, DOI:10.1038/s41557-021-00750-x.

8.Ye-Hui Chen, Heng-Hui Li, Xiao Zhang, Shao-Hua Xiang*, Shaoyu Li, Bin Tan*. Organocatalytic Enantioselective Synthesis of Atropisomeric Aryl-p-quinones: Platform Molecules for Diversity-oriented Synthesis of Biaryldiols. Angew. Chem. Int. Ed. 2020, 59, 11374.

9.Shao-Hua Xiang, Bin Tan*. Advances in Asymmetric Organocatalysis over the Last 10 Years. Nat. Commun. 2020, 11, 3786.

10.Shaoyu Li, Shao-Hua Xiang*, Bin Tan*. Chiral Phosphoric Acid Creates Promising Opportunities for Enantioselective Photoredox Catalysis. Chin. J. Chem. 2020, 38, 213.

11.Yong-Bin Wang, Quan-Hao Wu, Zhi-Peng Zhou, Shao-Hua Xiang*, Yuan Cui, Peiyuan Yu, Bin Tan*. Asymmetric Construction of Axially Chiral 2-Arylpyrroles by Chirality Transfer of Atropisomeric Alkenes. Angew. Chem. Int. Ed. 2019, 58, 13443.

12.Lin-Lin Zhang, Bing-Chao Da, Shao-Hua Xiang*, Shuai Zhu, Zi-Yun Yuan, Zhen Guo*, Bin Tan*. Organocatalytic Double Arylation of 3-Isothiocyanato Oxindoles: Stereocontrolled Synthesis of Complex Spirooxindoles. Tetrahedron 2019, 75, 1689.

13.Liang-Wen Qi, Shaoyu Li, Shao-Hua Xiang, Jun Wang*, Bin Tan*. Asymmetric Construction of Atropisomeric Biaryls via a Redox Neutral Cross-Coupling Strategy. Nat. Catal. 2019, 2, 314.

14.Lin-Lin Zhang, Ji-Wei Zhang, Shao-Hua Xiang*, Zhen Guo*, Bin Tan*. Remote Control of Axial Chirality: Synthesis of Spirooxindole-urazoles via Desymmetrization of ATAD. Org. Lett. 2018, 20, 6022.

15.Lin-Lin Zhang, Ji-Wei Zhang, Shao-Hua Xiang*, Zhen Guo*, Bin Tan*. Stereoselective Construction of Complex Spirooxindoles via Bisthiourea Catalyzed Three-component Reactions. Chin. J. Chem. 2018, 36, 1182.

16.Jian Zhang, Peiyuan Yu, Shao-Yu Li, He Sun, Shao-Hua Xiang, Jun Wang, Kendall N. Houk*, Bin Tan*. Asymmetric Phosphoric Acid-Catalyzed Four-Component Ugi Reaction. Science 2018, 361, eaas8708.

联系方式

xiangsh@sustech.edu.cn

13927406581